S-ADENOSYL-L-METHIONINE (SAMe) is an endogenous physiological molecule present in all body tissues and fluids. It is of fundamental importance in a number of biochemical reactions involving enzymatic transmethylation, contributing to the synthesis, to the activation and/or to the metabolism of compounds such as hormones, neurotransmitters, nucleic acids, proteins, phospholipids and some drugs. SAMe is considered to be a key metabolite that regulates the growth, death and differentiation of hepatocytes.

FUMITORY is a plant whose properties are useful for the well-being of the liver; Fumitory is mainly known for its hepatoprotective and depurative action; thanks to these properties it helps prevent the formation of gallstones and aids digestion. It mainly acts as a bile regulator and it has a beneficial effect on the entire gastro-intestinal tract. The active compounds, alkaloids, flavonoids and phenolic acids promote the body’s purifying actions.

MILK THISTLE When the liver is overloaded with toxins such as heavy metals and polluting substances, Milk Thistle supports its detoxifying process. This is mainly due to an active compound in milk thistle known as silymarin, which acts as an antioxidant by reducing the production of free radicals.

ZINC is present in the liver cells, so its deficiency can alter the functions of hepatocytes and also immune responses in inflammatory liver diseases, consequently causing a series of metabolic abnormalities, including insulin resistance, steatosis, iron overload.

SELENIUM With its antioxidant property can effectively alleviate metabolic disorders by mitigating oxidative stress and inflammatory response.

VITAMIN B6 supports the metabolism and repair of the liver and produces glutathione which is mainly present in the liver where it protects hepatocytes from particularly toxic molecules.